Dissecting the gene dose-effects of the APOE ε4 and ε2 alleles on hippocampal volumes in aging and Alzheimer's disease.
To investigate whether there is a specific dose-dependent effect of the Apolipoprotein E (APOE) ε4 and ε2 alleles on hippocampal volume, across the cognitive spectrum, from normal aging to Alzheimer's Disease (AD).We analyzed MR and genetic data on 662 patients from the Alzheimer's Disease...
Váldodahkkit: | , , , , |
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Materiálatiipa: | Artihkal |
Giella: | English |
Almmustuhtton: |
Public Library of Science (PLoS)
2013-01-01
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Ráidu: | PLoS ONE |
Liŋkkat: | http://europepmc.org/articles/PMC3566140?pdf=render |