Biotransformation of Agricultural Wastes into Lovastatin and Optimization of a Fermentation Process Using Response Surface Methodology (RSM)

Biotransformation of Agricultural Wastes into Lovastatin and Optimization of a Fermentation Process Using Response Surface Methodology (RSM)

Lovastatin is a competitive inhibitor of the enzyme 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA Reductase). The HMG-CoA reductase is responsible for the production of mevalonate by the reduction of HMG-CoA. It is a rate-limiting step in the production of cholesterol. The current study demonst...

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Bibliographic Details
Main Authors: Sadia Javed, Muhammad Azeem, Saqib Mahmood, Khalid Mashay Al-Anazi, Mohammad Abul Farah, Sajad Ali, Baber Ali
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Agronomy
Subjects:
lovastatin
agricultural wastes
sugarcane bagasse
<i>Aspergillus terreus</i> mutant
nuclear magnetic resonance (NMR)
X-ray diffraction (XRD)
Online Access:https://www.mdpi.com/2073-4395/12/11/2848

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https://www.mdpi.com/2073-4395/12/11/2848

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