Lysophosphatidic Acid Receptor 3 Promotes Mitochondrial Homeostasis against Oxidative Stress: Potential Therapeutic Approaches for Hutchinson–Gilford Progeria Syndrome

Lysophosphatidic Acid Receptor 3 Promotes Mitochondrial Homeostasis against Oxidative Stress: Potential Therapeutic Approaches for Hutchinson–Gilford Progeria Syndrome

Lysophosphatidic acid (LPA) is a growth factor-like lipid mediator that regulates various physiological functions via activation of multiple LPA G protein-coupled receptors. We previously reported that LPA suppresses oxidative stress in premature aging Hutchinson-Gilford progeria syndrome (HGPS) pat...

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Bibliographic Details
Main Authors: Jui-Chung Chiang, Wei-Min Chen, Ciara Newman, Benjamin P. C. Chen, Hsinyu Lee
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Antioxidants
Subjects:
lysophosphatidic acid
mitochondrial homeostasis
oxidative stress
Hutchinson-Gilford progeria syndrome
Online Access:https://www.mdpi.com/2076-3921/11/2/351

Internet

https://www.mdpi.com/2076-3921/11/2/351

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