Optimization of the Process of Cholera Chemical Pelleted Vaccine Production Using Ultrafiltration Technology

Technology of O-antigen obtaining from Vibrio cholerae M41production strain, using the hollow fiber ultrafiltration modules, is developed and introduced into cholera vaccine manufacturing. Application of ultrafiltration makes it possible to obtain native high-activity O-antigen preparations which co...

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Bibliographic Details
Main Authors: O. V. Gromova, S. A. Nizhegorodtsev, I. A. Dyatlov, V. V. Kutyrev
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2011-06-01
Series:Проблемы особо опасных инфекций
Subjects:
Online Access:https://journal.microbe.ru/jour/article/view/686