Functional cure of a chronic virus infection by shifting the virus - host equilibrium state

Functional cure of a chronic virus infection by shifting the virus - host equilibrium state

The clinical handling of chronic virus infections remains a challenge. Here we describe recent progress in the understanding of virus - host interaction dynamics. Based on the systems biology concept of multi-stability and the prediction of multiplicative cooperativity between virus-specific cytotox...

Full description

Bibliographic Details
Main Authors: Gennady Bocharov, Dmitry Grebennikov, Paula Cebollada Rica, Eva Domenjo-Vila, Valentina Casella, Andreas Meyerhans
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
Chronic virus infections
multi-stability
shifting equilibrium states
cure strategies
LCMV (lymphocytic choriomeningitis virus)
HIV (human immunodeficiency virus)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.904342/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.904342/full

Similar Items