A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1.

A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1.

Human arylamine N-acetyltransferase 1 (hNAT1) has become an attractive potential biomarker for estrogen-receptor-positive breast cancers. We describe here the mechanism of action of a selective non-covalent colorimetric biosensor for the recognition of hNAT1 and its murine homologue, mNat2, over the...

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Bibliographic Details
Main Authors: Nicola Laurieri, James E Egleton, Amy Varney, Cyrille C Thinnes, Camilo E Quevedo, Peter T Seden, Sam Thompson, Fernando Rodrigues-Lima, Julien Dairou, Jean-Marie Dupret, Angela J Russell, Edith Sim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3734253?pdf=render

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http://europepmc.org/articles/PMC3734253?pdf=render

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