Alternative adenosine Receptor activation: The netrin-Adora2b link

Alternative adenosine Receptor activation: The netrin-Adora2b link

During hypoxia or inflammation, extracellular adenosine levels are elevated. Studies using pharmacologic approaches or genetic animal models pertinent to extracellular adenosine signaling implicate this pathway in attenuating hypoxia-associated inflammation. There are four distinct adenosine recepto...

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Bibliographic Details
Main Authors: Xiaoyi Yuan, Tingting Mills, Marie-Francoise Doursout, Scott E. Evans, Marcos F. Vidal Melo, Holger K. Eltzschig
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
adenosine
netrin-1
Adora2b
hypoxia
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.944994/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.944994/full

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