Regulation of TRIB1 abundance in hepatocyte models in response to proteasome inhibition

Abstract Tribbles related homolog 1 (TRIB1) contributes to lipid and glucose homeostasis by facilitating the degradation of cognate cargos by the proteasome. In view of the key metabolic role of TRIB1 and the impact of proteasome inhibition on hepatic function, we continue our exploration of TRIB1 r...

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Bibliographic Details
Main Authors: Sébastien Soubeyrand, Paulina Lau, Ruth McPherson
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36512-7