Regulation of TRIB1 abundance in hepatocyte models in response to proteasome inhibition
Abstract Tribbles related homolog 1 (TRIB1) contributes to lipid and glucose homeostasis by facilitating the degradation of cognate cargos by the proteasome. In view of the key metabolic role of TRIB1 and the impact of proteasome inhibition on hepatic function, we continue our exploration of TRIB1 r...
Main Authors: | Sébastien Soubeyrand, Paulina Lau, Ruth McPherson |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-36512-7 |
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