Remodeling of the Dermal Extracellular Matrix in a Tissue-Engineered Psoriatic Skin Model by n-3 Polyunsaturated Fatty Acids

Remodeling of the Dermal Extracellular Matrix in a Tissue-Engineered Psoriatic Skin Model by n-3 Polyunsaturated Fatty Acids

Psoriasis is an inflammatory skin disease mainly associated with an epidermal disorder. However, the involvement of the dermal extracellular matrix (ECM) composition in psoriasis is still poorly understood. This study aimed to investigate the expression of ECM components in psoriatic skin substitute...

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Bibliographic Details
Main Authors: Mélissa Simard, Alexe Grenier, Geneviève Rioux, Andréa Tremblay, Isalie Blais, Nicolas Flamand, Roxane Pouliot
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
psoriasis
inflammatory disease
n-3 PUFA
alpha-linolenic acid
bioactive lipid mediators
extracellular matrix
Online Access:https://www.mdpi.com/2227-9059/10/5/1078

Internet

https://www.mdpi.com/2227-9059/10/5/1078

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