Resistance to aztreonam-avibactam due to a mutation of SHV-12 in Enterobacter

Abstract Aztreonam-avibactam is an important option against Enterobacterales producing metallo-β-lactamases (MBLs). We obtained an aztreonam-avibactam-resistant mutant of an MBL-producing Enterobacter mori strain by induced mutagenesis. Genome sequencing revealed an Arg244Gly (Ambler position) subst...

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Bibliographic Details
Main Authors: Shikai Wu, Ke Ma, Yu Feng, Zhiyong Zong
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Online Access:https://doi.org/10.1186/s12941-023-00605-y