The Human Microbiome and the Missing Heritability Problem

The Human Microbiome and the Missing Heritability Problem

The “missing heritability” problem states that genetic variants in Genome-Wide Association Studies (GWAS) cannot completely explain the heritability of complex traits. Traditionally, the heritability of a phenotype is measured through familial studies using twins, siblings and other close relatives,...

Full description

Bibliographic Details
Main Authors: Santiago Sandoval-Motta, Maximino Aldana, Esperanza Martínez-Romero, Alejandro Frank
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Genetics
Subjects:
missing heritability
GWAS (genome-wide association studies)
MWAS (metagenome-wide association studies)
microbiome
holobiont ecology
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00080/full

Internet

http://journal.frontiersin.org/article/10.3389/fgene.2017.00080/full

Similar Items