Improved simultaneous quantitation of candesartan and hydrochlorthiazide in human plasma by UPLCâMS/MS and its application in bioequivalence studies

A validated ultra-performance liquid chromatography mass spectrometric method (UPLCâMS/MS) was used for the simultaneous quantitation of candesartan (CN) and hydrochlorothiazide (HCT) in human plasma. The analysis was performed on UPLCâMS/MS system using turbo ion spray interface. Negative ions were...

Full description

Bibliographic Details
Main Authors: Bhupinder Singh, Rama S. Lokhandae, Ashish Dwivedi, Sandeep Sharma, Naveen Dubey
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177913000579