2: Genetic- and Mobilization-Based Alterations in Matrix Alignment to Mitigate Aberrant Cell Fate Determination

Purpose: Cells recognize mechanical cues from the extracellular environment through interactions with matrix proteins, such as collagen. Following injury, fibrotic deposition of collagen can lead to aberrant cell differentiation and failed healing. Aligned collagen matrices can drive PDGFRα+ mesench...

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Bibliographic Details
Main Authors: Chase A. Pagani, BA, Amy L. Strong, MD/PhD, Nicholas Livingston, BA, Yuxiao Sun, PhD, Geoffrey E. Hespe, MD, Johanna Nunez, MD, Nicole Patel, BS, Amanda K. Huber, PhD, Chunxi Ge, PhD, Renny Franceschi, PhD, Benjamin Levi, MD
Format: Article
Language:English
Published: Wolters Kluwer 2021-07-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/01.GOX.0000769932.69148.04