2: Genetic- and Mobilization-Based Alterations in Matrix Alignment to Mitigate Aberrant Cell Fate Determination
Purpose: Cells recognize mechanical cues from the extracellular environment through interactions with matrix proteins, such as collagen. Following injury, fibrotic deposition of collagen can lead to aberrant cell differentiation and failed healing. Aligned collagen matrices can drive PDGFRα+ mesench...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2021-07-01
|
Series: | Plastic and Reconstructive Surgery, Global Open |
Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/01.GOX.0000769932.69148.04 |