Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer

Abstract Molecular biology achieves control over complex reaction networks by means of molecular systems that translate a chemical input (such as ligand binding) into an orthogonal chemical output (such as acylation or phosphorylation). We present an artificial molecular translation device that conv...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: David P. Tilly, Jean-Paul Heeb, Simon J. Webb, Jonathan Clayden
التنسيق: مقال
اللغة:English
منشور في: Nature Portfolio 2023-05-01
سلاسل:Nature Communications
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-023-38339-2