Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer

Abstract Molecular biology achieves control over complex reaction networks by means of molecular systems that translate a chemical input (such as ligand binding) into an orthogonal chemical output (such as acylation or phosphorylation). We present an artificial molecular translation device that conv...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: David P. Tilly, Jean-Paul Heeb, Simon J. Webb, Jonathan Clayden
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Nature Portfolio 2023-05-01
Цуврал:Nature Communications
Онлайн хандалт:https://doi.org/10.1038/s41467-023-38339-2