Tumor cell death mediated by peptides that recognize branched intermediates of DNA replication and repair.

Effective treatments for cancer are still needed, both for cancers that do not respond well to current therapeutics and for cancers that become resistant to available treatments. Herein we investigated the effect of a structure-selective d-amino acid peptide wrwycr that binds replication fork mimics...

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Bibliographic Details
Main Authors: Mamon Dey, Sukanya Patra, Leo Y Su, Anca M Segall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3828334?pdf=render