Marine-Derived Lead Fascaplysin: Pharmacological Activity, Total Synthesis, and Structural Modification

Marine-Derived Lead Fascaplysin: Pharmacological Activity, Total Synthesis, and Structural Modification

Fascaplysin is a planar structure pentacyclic alkaloid isolated from sponges, which can effectively induce the apoptosis of cancer cells. In addition, fascaplysin has diverse biological activities, such as antibacterial, anti-tumor, anti-plasmodium, etc. Unfortunately, the planar structure of fascap...

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Bibliographic Details
Main Authors: Chao Wang, Siyuan Wang, Haonan Li, Yonglian Hou, Hao Cao, Huiming Hua, Dahong Li
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Marine Drugs
Subjects:
marine alkaloid
fascaplysin
synthetic chemistry
anti-tumor
Online Access:https://www.mdpi.com/1660-3397/21/4/226

Internet

https://www.mdpi.com/1660-3397/21/4/226

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