Genomic 5-mC contents in peripheral blood leukocytes were independent protective factors for coronary artery disease with a specific profile in different leukocyte subtypes

Genomic 5-mC contents in peripheral blood leukocytes were independent protective factors for coronary artery disease with a specific profile in different leukocyte subtypes

Abstract Background Alterations in DNA methylation are demonstrated in atherosclerosis pathogenesis. However, changing rules of global DNA methylation and hydroxymethylation in peripheral blood leukocytes (PBLs) and different blood cell subtypes of coronary artery disease (CAD) patients are still in...

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Bibliographic Details
Main Authors: Qianyun Deng, Wei Huang, Chunyan Peng, Jiajia Gao, Zuhua Li, Xueping Qiu, Na Yang, Bifeng Yuan, Fang Zheng
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Clinical Epigenetics
Subjects:
Mass spectrometry
5-Methylcytosine
5-Hydroxymethylcytosine
Peripheral blood leukocytes
Coronary artery disease
Online Access:http://link.springer.com/article/10.1186/s13148-018-0443-x

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http://link.springer.com/article/10.1186/s13148-018-0443-x

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