Pectolinarigenin alleviated septic acute kidney injury via inhibiting Jak2/Stat3 signaling and mitochondria dysfunction

Pectolinarigenin alleviated septic acute kidney injury via inhibiting Jak2/Stat3 signaling and mitochondria dysfunction

Sepsis is a systemic inflammatory response to infection, where sepsis-associated acute kidney injury (AKI) is a common morbid disease with a high morbidity and mortality, and however at present no effective therapy exists. Increasing evidence have shown that mitochondrial damage and inflammatory res...

Full description

Bibliographic Details
Main Authors: Zhouke Tan, Qianqian Liu, Hongjun Chen, Ziyang Zhang, Qin Wang, Yingsong Mu, Yiman Li, TingTing Hu, Yibin Yang, Xiaoyong Yan
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Sepsis
Acute kidney injury
Pectolinarigenin
Mitochondria dysfunction
Jak2/Stat3
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223000744

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223000744

Similar Items