The Impact of Epithelial–Mesenchymal Transition and Metformin on Pancreatic Cancer Chemoresistance: A Pathway towards Individualized Therapy

Globally, pancreatic ductal adenocarcinoma remains among the most aggressive forms of neoplastic diseases, having a dismal prognostic outcome. Recent findings elucidated that epithelial–mesenchymal transition (EMT) can play an important role in pancreatic tumorigenic processes, as it contributes to...

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Bibliographic Details
Main Authors: Aiste Gulla, Urte Andriusaityte, Gabrielius Tomas Zdanys, Elena Babonaite, Kestutis Strupas, Helena Kelly
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/58/4/467