GABA and Combined GABA with GAD65-Alum Treatment Alters Th1 Cytokine Responses of PBMCs from Children with Recent-Onset Type 1 Diabetes

GABA and Combined GABA with GAD65-Alum Treatment Alters Th1 Cytokine Responses of PBMCs from Children with Recent-Onset Type 1 Diabetes

Type 1 diabetes (T1D) is an autoimmune disease culminating in the destruction of insulin-producing pancreatic cells. There is a need for the development of novel antigen-specific strategies to delay cell destruction, including combinatorial strategies that do not elicit systemic immunosuppression. G...

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Bibliographic Details
Main Authors: Katie E. Heath, Joseph M. Feduska, Jared P. Taylor, Julie A. Houp, Davide Botta, Frances E. Lund, Gail J. Mick, Gerald McGwin, Kenneth L. McCormick, Hubert M. Tse
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomedicines
Subjects:
type 1 diabetes
GABA
autoimmunity
GAD65
cytokine
Online Access:https://www.mdpi.com/2227-9059/11/7/1948

Internet

https://www.mdpi.com/2227-9059/11/7/1948

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