Aromatic disulfides as potential inhibitors against interaction between deaminase APOBEC3G and HIV infectivity factor

Aromatic disulfides as potential inhibitors against interaction between deaminase APOBEC3G and HIV infectivity factor

APOBEC3G (A3G) is a member of cytosine deaminase family with a variety of innate immune functions. It displays activities against retrovirus and retrotransposon by inhibition of virus infectivity factor (Vif)-deficient HIV-1 replication. The interaction between A3G N-terminal domain and Vif directs...

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Bibliographic Details
Main Authors: Yan Xiaoxuan, Chen Chao, Wang Chunxi, Lan Wenxian, Wang Jianguo, Cao Chunyang
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-05-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
APOBEC3G
Vif
interaction
HIV-1
aromatic disulfide
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022049

Internet

https://www.sciengine.com/doi/10.3724/abbs.2022049

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