Application of Pt@ZIF-8 nanocomposite-based electrochemical biosensor for sensitive diagnosis of tau protein in Alzheimer’s disease patients

Abstract Alzheimer’s disease (AD) is a progressive brain disorder characterized by the ongoing decline of brain functions. Studies have revealed the detrimental effects of hyperphosphorylated tau (p-tau) protein fibrils in AD pathogenesis, highlighting the importance of this factor in the early-stag...

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Bibliographic Details
Main Authors: Forough Chakari-Khiavi, Arezoo Mirzaie, Balal Khalilzadeh, Hadi Yousefi, Rozita Abolhasan, Amin Kamrani, Ramin Pourakbari, Koorosh Shahpasand, Mehdi Yousefi, Mohammad-Reza Rashidi
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43180-0