Polygenic risk scores in the clinic: Translating risk into action

Summary: Polygenic risk scores (PRSs) are heralded as useful tools for risk stratification and personalized preventive care, but they are clinically useful only if they can be translated into action. The risk information conveyed by a PRS must be contextualized to enable this. Best practices are evo...

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Bibliographic Details
Main Authors: Anna C.F. Lewis, Robert C. Green, Jason L. Vassy
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:HGG Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247721000282