Long-term outcome of progressive multifocal leukoencephalopathy with recombinant interleukin-2 treatment and an associated increase in the number of HPyV-2-specific T-cells: a case report

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by reactivation of the human polyomavirus 2 (HPyV-2). PML is associated with a high morbidity and mortality rate and there is currently no standard curative therapy. We report short-term immunologic response and long-...

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Bibliographic Details
Main Authors: Fieke W. Hoff, John Rolwes, Paula A. Hardeman, Molly Perkins, Eugene O. Major, Daniel Douek, Robert H. Collins, Benjamin M. Greenberg
Format: Article
Language:English
Published: SAGE Publishing 2023-10-01
Series:Therapeutic Advances in Hematology
Online Access:https://doi.org/10.1177/20406207231201721