MarkerMap: nonlinear marker selection for single-cell studies

Abstract Single-cell RNA-seq data allow the quantification of cell type differences across a growing set of biological contexts. However, pinpointing a small subset of genomic features explaining this variability can be ill-defined and computationally intractable. Here we introduce MarkerMap, a gene...

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Bibliographic Details
Main Authors: Wilson Gregory, Nabeel Sarwar, George Kevrekidis, Soledad Villar, Bianca Dumitrascu
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-024-00339-3