Hypoallergenic Wheat Line (1BS-18H) Lacking ω5-Gliadin Induces Oral Tolerance to Wheat Gluten Proteins in a Rat Model of Wheat Allergy

Hypoallergenic Wheat Line (1BS-18H) Lacking ω5-Gliadin Induces Oral Tolerance to Wheat Gluten Proteins in a Rat Model of Wheat Allergy

The early ingestion of food can prevent the onset of food allergy related to inducing oral tolerance (OT). We developed the Hokushin wheat line as a hypoallergenic wheat (1BS-18H) lacking ω5-gliadin, a major allergen of wheat-dependent exercise-induced anaphylaxis (WDEIA). The 1BS-18H wheat had lowe...

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Bibliographic Details
Main Authors: Yukinori Yamada, Tomoharu Yokooji, Kyohei Kunimoto, Koki Inoguchi, Ryohei Ogino, Takanori Taogoshi, Eishin Morita, Hiroaki Matsuo
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Foods
Subjects:
gluten
ω5-gliadin
hypoallergenic wheat
oral tolerance
wheat allergy
Online Access:https://www.mdpi.com/2304-8158/11/15/2181

Internet

https://www.mdpi.com/2304-8158/11/15/2181

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