SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with the N-glycolyl GM3-specific anti-tumor antibody 14F7

SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with the N-glycolyl GM3-specific anti-tumor antibody 14F7

Cancer immunotherapy represents a promising approach to specifically target and treat cancer. The most common mechanisms by which monoclonal antibodies kill cells include antibody-dependent cell-mediated cytotoxicity, complement-dependent cytotoxicity and apoptosis, but also other mechanisms have be...

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Bibliographic Details
Main Authors: Paula A. Bousquet, Dipankar Manna, Joe A. Sandvik, Magnus Ø. Arntzen, Ernesto Moreno, Kirsten Sandvig, Ute Krengel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
cytoskeleton
NeuGc GM3/Neu5Gc GM3
14F7
SILAC
transcription factors
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.994790/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.994790/full

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