A High Level of Intestinal Alkaline Phosphatase Is Protective Against Type 2 Diabetes Mellitus Irrespective of Obesity

A High Level of Intestinal Alkaline Phosphatase Is Protective Against Type 2 Diabetes Mellitus Irrespective of Obesity

Mice deficient in intestinal alkaline phosphatase (IAP) develop type 2 diabetes mellitus (T2DM). We hypothesized that a high level of IAP might be protective against T2DM in humans. We determined IAP levels in the stools of 202 diabetic patients and 445 healthy non-diabetic control people. We found...

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Bibliographic Details
Main Author: Madhu S. Malo
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:EBioMedicine
Subjects:
Fatty liver
Glucose intolerance
Hypertension
Incipient diabetes
Insulin resistance
The metabolic syndrome
Obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415302115

Internet

http://www.sciencedirect.com/science/article/pii/S2352396415302115

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