Combinatory repair strategy to promote axon regeneration and functional recovery after chronic spinal cord injury

Abstract Eight weeks post contusive spinal cord injury, we built a peripheral nerve graft bridge (PNG) through the cystic cavity and treated the graft/host interface with acidic fibroblast growth factor (aFGF) and chondroitinase ABC (ChABC). This combinatorial strategy remarkably enhanced integratio...

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Bibliographic Details
Main Authors: Marc A. DePaul, Ching-Yi Lin, Jerry Silver, Yu-Shang Lee
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09432-6