Loss of Endothelial Glycocalyx Hyaluronan Impairs Endothelial Stability and Adaptive Vascular Remodeling after Arterial Ischemia

Loss of Endothelial Glycocalyx Hyaluronan Impairs Endothelial Stability and Adaptive Vascular Remodeling after Arterial Ischemia

We recently reported that loss of hyaluronan (HA) from the endothelial glycocalyx leads to loss of vessel stability in specific microcirculatory vascular beds. Here we hypothesized that such derangements in the glycocalyx may also impair the adaptive response to vascular ischemia. Endothelial specif...

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Bibliographic Details
Main Authors: Gangqi Wang, Margreet R. de Vries, Wendy M. P. J. Sol, Annemarie M. van Oeveren-Rietdijk, Hetty C. de Boer, Anton Jan van Zonneveld, Paul H. A. Quax, Ton J. Rabelink, Bernard M. van den Berg
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
hyaluronan
endothelial glycocalyx
angiogenesis
diabetes
Online Access:https://www.mdpi.com/2073-4409/9/4/824

Internet

https://www.mdpi.com/2073-4409/9/4/824

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