Case report: Use of granulocyte-colony stimulating factor as an immunomodulatory therapy in a patient with neuromyelitis optica spectrum disorder and comorbid immunodeficiency

Case report: Use of granulocyte-colony stimulating factor as an immunomodulatory therapy in a patient with neuromyelitis optica spectrum disorder and comorbid immunodeficiency

BackgroundAutoimmune diseases can coexist with immunodeficiency. We describe a treatment approach in which granulocyte-colony stimulating factor (G-CSF) is used to restore immune competence without worsening autoimmunity. G-CSF is a polyfunctional cytokine that influences survival, proliferation, an...

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Bibliographic Details
Main Authors: Gina S. Perez Giraldo, Edith L. Graham, Stephen VanHaerents, Roumen Balabanov
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Neurology
Subjects:
neuromyelitis optica spectrum disorder
immunodeficiency
autoimmunity
granulocyte-colony stimulating factor
immunomodulation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1240356/full

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https://www.frontiersin.org/articles/10.3389/fneur.2023.1240356/full

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