Peripheral blood mononuclear cell mitochondrial dysfunction in acute alcohol‐associated hepatitis

Peripheral blood mononuclear cell mitochondrial dysfunction in acute alcohol‐associated hepatitis

Abstract Background Patients with acute alcohol‐associated hepatitis (AH) have immune dysfunction. Mitochondrial function is critical for immune cell responses and regulates senescence. Clinical translational studies using complementary bioinformatics‐experimental validation of mitochondrial respons...

Full description

Bibliographic Details
Main Authors: Annette Bellar, Nicole Welch, Jaividhya Dasarathy, Amy Attaway, Ryan Musich, Avinash Kumar, Jinendiran Sekar, Saurabh Mishra, Yana Sandlers, David Streem, Laura E Nagy, Srinivasan Dasarathy
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Clinical and Translational Medicine
Subjects:
alcohol‐associated hepatitis
immune senescence
intermediary metabolites
mitochondrial oxidation
peripheral blood mononuclear cells
single‐cell RNA sequencing
Online Access:https://doi.org/10.1002/ctm2.1276

Internet

https://doi.org/10.1002/ctm2.1276

Similar Items