Nanoarchitectured conjugates targeting angiogenesis: investigating heparin-taurocholate acid conjugates (LHT7) as an advanced anti-angiogenic therapy for brain tumor treatment

Abstract Background Glioblastoma is a highly malignant brain tumor associated with poor prognosis. Conventional therapeutic approaches have limitations due to their toxic effects on normal tissue and the development of tumor cell resistance. This study aimed to explore alternative mechanisms for gli...

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Bibliographic Details
Main Authors: Hyung Shik Kim, Jae Hak Seol, Hae Hyun Hwang, Dong Yun Lee
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-09-01
Series:Biomaterials Research
Subjects:
Online Access:https://doi.org/10.1186/s40824-023-00420-8