RNA elements in open reading frames of the bluetongue virus genome are essential for virus replication.

Members of the Reoviridae family are non-enveloped multi-layered viruses with a double stranded RNA genome consisting of 9 to 12 genome segments. Bluetongue virus is the prototype orbivirus (family Reoviridae, genus Orbivirus), causing disease in ruminants, and is spread by Culicoides biting midges....

Full description

Bibliographic Details
Main Authors: Femke Feenstra, René G P van Gennip, Sandra G P van de Water, Piet A van Rijn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3962428?pdf=render