Preptin Deficiency Does Not Protect against High‐Fat Diet‐Induced Metabolic Dysfunction or Bone Loss in Mice

Preptin Deficiency Does Not Protect against High‐Fat Diet‐Induced Metabolic Dysfunction or Bone Loss in Mice

ABSTRACT Preptin is derived from the cleavage of the E‐peptide of pro‐insulin‐like growth factor (IGF)‐II and is an insulin secretagogue. Observational studies have linked elevated circulating preptin to metabolic dysfunction in humans; however, a causal role for preptin in metabolic dysfunction has...

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Bibliographic Details
Main Authors: Emma J. Buckels, Joey Tan, Huai‐Ling Hsu, Yuting Zhu, Christina M. Buchanan, Brya G. Matthews, Kate L. Lee
Format: Article
Language:English
Published: Oxford University Press 2023-08-01
Series:JBMR Plus
Subjects:
DIET
GLUCOSE TOLERANCE
INSULIN‐LIKE GROWTH FACTOR‐II
METABOLIC DYSFUNCTION
SECRETAGOGUE
SEXUAL DIMORPHISM
Online Access:https://doi.org/10.1002/jbm4.10777

Internet

https://doi.org/10.1002/jbm4.10777

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