Extension of the Generalized Disequilibrium Test to polytomous phenotypes and two-locus models
We extend the usual logistic model between a dichotomous phenotype and an allele count in two ways: a polytomous phenotype with K > 2 levels, and modelling of allele counts at two unlinked marker loci. Inference is based on within-family information to guard against potential bias due to populati...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-08-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00258/full |