An Open-Source AI Framework for the Analysis of Single Cells in Whole-Slide Images with a Note on CD276 in Glioblastoma

An Open-Source AI Framework for the Analysis of Single Cells in Whole-Slide Images with a Note on CD276 in Glioblastoma

Routine examination of entire histological slides at cellular resolution poses a significant if not insurmountable challenge to human observers. However, high-resolution data such as the cellular distribution of proteins in tissues, e.g., those obtained following immunochemical staining, are highly...

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Bibliographic Details
Main Authors: Islam Alzoubi, Guoqing Bao, Rong Zhang, Christina Loh, Yuqi Zheng, Svetlana Cherepanoff, Gary Gracie, Maggie Lee, Michael Kuligowski, Kimberley L. Alexander, Michael E. Buckland, Xiuying Wang, Manuel B. Graeber
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
artificial intelligence
bifocal convolutional neural network (BCNN)
CD276
image fusion
image segmentation
PathoFusion framework
Online Access:https://www.mdpi.com/2072-6694/14/14/3441

Internet

https://www.mdpi.com/2072-6694/14/14/3441

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