Purification, characterization, and expression of rat intestinal alkaline sphingomyelinase

Intestinal alkaline sphingomyelinase (SMase) has physiological roles in the digestion of sphingomyelin (SM) and clinical implications in colonic carcinogenesis. In the present work, the enzyme from rat has been purified 1,589-fold with 11% recovery by elution of the intestine with bile salt, precipi...

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Bibliographic Details
Main Authors: Yajun Cheng, Åke Nilsson, Elisabeth Tömquist, Rui-Dong Duan
Format: Article
Language:English
Published: Elsevier 2002-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301747