Nitrile Oxide, Alkenes, Dipolar Cycloaddition, Isomerization and Metathesis Involved in the Syntheses of 2-Isoxazolines

Nitrile Oxide, Alkenes, Dipolar Cycloaddition, Isomerization and Metathesis Involved in the Syntheses of 2-Isoxazolines

The involvement of 1,3-dipolar cycloaddition (1,3-DP), double bond migration, metathesis, and nitrile oxide (including in situ-generated nitrile oxide) as dipoles, together with the C=C bond containing dipolarophiles, in the syntheses of 2-isoxazolines is presented. Methods for synthesizing isoxazol...

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Bibliographic Details
Main Authors: Stanisław Krompiec, Piotr Lodowski, Aneta Kurpanik-Wójcik, Bogumiła Gołek, Angelika Mieszczanin, Aleksandra Fijołek, Marek Matussek, Klaudia Kaszuba
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
2-isoxazolines
nitrile oxide
1,3-dipolar cycloaddition
allyl compounds
reaction mechanism
isoxazolines in pharmacy
Online Access:https://www.mdpi.com/1420-3049/28/6/2547

Internet

https://www.mdpi.com/1420-3049/28/6/2547

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