De novo actin polymerization is required for model Hirano body formation in Dictyostelium
Hirano bodies are eosinophilic, actin-rich inclusions found in autopsied brains in numerous neurodegenerative diseases. The mechanism of Hirano body formation is unknown. Mass spectrometry analysis was performed to identify proteins from partially purified model Hirano bodies from Dictyostelium. Thi...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2016-06-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/5/6/807 |