Role of TRPC3 in Right Ventricular Dilatation under Chronic Intermittent Hypoxia in 129/SvEv Mice

Role of TRPC3 in Right Ventricular Dilatation under Chronic Intermittent Hypoxia in 129/SvEv Mice

Patients with obstructive sleep apnea (OSA) exhibit a high prevalence of pulmonary hypertension and right ventricular (RV) hypertrophy. However, the exact molecule responsible for the pathogenesis remains unknown. Given the resistance to RV dilation observed in transient receptor potential canonical...

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Bibliographic Details
Main Authors: Do-Yang Park, Woon Heo, Miran Kang, Taeyoung Ahn, DoHyeon Kim, Ayeon Choi, Lutz Birnbaumer, Hyung-Ju Cho, Joo Young Kim
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
obstructive sleep apnea
chronic intermittent hypoxia
transient receptor potential cation channel 3
right ventricle
right ventricle hypertrophy
right ventricle dilation
Online Access:https://www.mdpi.com/1422-0067/24/14/11284

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https://www.mdpi.com/1422-0067/24/14/11284

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