Characterizing the role of SLC3A2 in the molecular landscape and immune microenvironment across human tumors

Background: Inducing ferroptosis in human tumors has become a potential strategy to improve the prognosis of patients, even in those with chemotherapeutic resistance. The xCT complex is a major target for ferroptosis induction, constituted by SLC7A11 and SLC3A2. The role of SLC7A11 in cancer has bee...

Full description

Bibliographic Details
Main Authors: Jiajun He, Dong Liu, Mei Liu, Rong Tang, Dongqing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.961410/full