A genome-wide search of Toll/Interleukin-1 receptor (TIR) domain-containing adapter molecule (TICAM) and their evolutionary divergence from other TIR domain containing proteins

Abstract Toll/Interleukin-1 receptor (TIR) domains are cytoplasmic domain that mediates receptor signalling. These domains are present in proteins like Toll-like receptors (TLR), its signaling adaptors and Interleukins, that form a major part of the immune system. These TIR domain containing signali...

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Bibliographic Details
Main Authors: Shailya Verma, Ramanathan Sowdhamini
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Biology Direct
Subjects:
Online Access:https://doi.org/10.1186/s13062-022-00335-9