Construction and validation of chemoresistance-associated tumor- infiltrating exhausted-like CD8+ T cell signature in breast cancer: cr-TILCD8TSig

Construction and validation of chemoresistance-associated tumor- infiltrating exhausted-like CD8+ T cell signature in breast cancer: cr-TILCD8TSig

BackgroundAccumulating evidence has revealed that CD8+ T cell exhaustion (Tex) results in worse immunotherapy outcomes. However, the molecular functions and mechanisms of action of Tex in chemoresistance needed to be elucidated.MethodsThe populations of tumor-infiltrating CD8+ T cells (TILCD8Ts) in...

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Bibliographic Details
Main Authors: DQ. Cai, Diankui Cai, Yiping Zou, Xumeng Chen, Zhixiang Jian, Mude Shi, Ye Lin, Jueming Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
prognosis
chemoresistance
immunotherapy
signature
tumor-infiltrating CD8+ T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1120886/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1120886/full

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