In situ copper photocatalysts triggering halide atom transfer of unactivated alkyl halides for general C(sp3)-N couplings

Abstract Direct reduction of unactivated alkyl halides for C(sp3)-N couplings under mild conditions presents a significant challenge in organic synthesis due to their low reduction potential. Herein, we introduce an in situ formed pyridyl-carbene-ligated copper (I) catalyst that is capable of abstra...

Full description

Bibliographic Details
Main Authors: Hang Luo, Yupeng Yang, Yukang Fu, Fangnian Yu, Lei Gao, Yunpeng Ma, Yang Li, Kaifeng Wu, Luqing Lin
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-50082-w