H3K27me3 at pericentromeric heterochromatin is a defining feature of the early mouse blastocyst

Abstract Early mouse development is characterized by structural and epigenetic changes while cells progress towards differentiation. At blastocyst stage, the segregation of the three primordial lineages is accompanied by establishment of differential patterns of DNA methylation and post-translationa...

Full description

Bibliographic Details
Main Authors: Mélanie Pailles, Mélanie Hirlemann, Vincent Brochard, Martine Chebrout, Jean-François Oudin, Hendrik Marks, Alice Jouneau, Amélie Bonnet-Garnier
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17730-x