Investigation of PM2.5-induced carcinogenic effects through mediation of ErbB family based on DNA methylation and transcriptomics analysis by a lung-mimicking microfluidic platform

Investigation of PM2.5-induced carcinogenic effects through mediation of ErbB family based on DNA methylation and transcriptomics analysis by a lung-mimicking microfluidic platform

Fine particle (PM2.5, less than 2.5 micrometers in diameter) is regarded as a harmful carcinogen. However, the molecular mechanisms of the carcinogenic effects of ambient fine particles have not been fully elucidated, and therapeutic options to address this major public health challenge are lacking....

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Bibliographic Details
Main Authors: Lulu Zheng, Yuwen Wang, Yule Zhang, Zongtao Chai, Sixiu Liu, Bo Wang, Bo Dai, Dawei Zhang
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
ErbB family
Inhibitors
Carcinogenic effects
PM2.5
Microfluidic chip
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322011587

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http://www.sciencedirect.com/science/article/pii/S0147651322011587

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