Expression of T-Bet, Eomesodermin, and GATA-3 Correlates With Distinct Phenotypes and Functional Properties in Porcine γδ T Cells

Expression of T-Bet, Eomesodermin, and GATA-3 Correlates With Distinct Phenotypes and Functional Properties in Porcine γδ T Cells

Unlike mice and humans, porcine γδ T cells represent a prominent subset of T cells in blood and secondary lymphatic organs. GATA-3, T-bet and Eomesodermin (Eomes) are transcription factors with crucial functions in T-cell development and functional differentiation, but their expression has not been...

Full description

Bibliographic Details
Main Authors: Irene M. Rodríguez-Gómez, Stephanie C. Talker, Tobias Käser, Maria Stadler, Lisa Reiter, Andrea Ladinig, Jemma V. Milburn, Sabine E. Hammer, Kerstin H. Mair, Armin Saalmüller, Wilhelm Gerner
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
γδ T cells
swine
pig
T-bet
Eomes
GATA-3
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00396/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00396/full

Similar Items